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https://www.connsante.com/custom_118360.html 期刊論文 期刊論文 1.Yang CC, Hsu CP, Sheu JC, Mai XY, Yang SD. Differential tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA /GSK-3α in well and poorly differentiated human prostate carcinoma cells. J Protein Chem 17: 329-335 (1998). 2.Yang SD, Yu JS, Yang CC, Lee SC, Lee TT, Ni MH, Kuan CY, Chen HC. Overexpression of protein kinase FA/GSK-3α (a proline-directed protein kinase) correlates with human hepatoma dedifferentiation/progression. J Cell Biochem 61: 238-245 (1995). 3.Lee TT, Ho YS, Yu JS, Yang SD. Overexpression of cellular activity and protein level of protein kinase FA/GSK-3α correlates with human thyroid tumor cell dedifferentiation. J Cell Biochem 58: 474-480 (1995). 4.Yang SD, Yu JS, Lee TT, Ni MH, Yang CC, Ho YS, Tsen TZ. Association of protein kinase FA/GSK-3alpha (a proline-directed kinase and a regulator of protooncogenes) with human cervical carcinoma dedifferentiation/progression. J Cell Biochem 59: 143-150 (1995). 5.Banerji, V., Frumm, S.M., Ross, K.N., Li, L.S., Schinzel, A.C., Hahn, C.K., Kakoza, R.M., Chow, K.T., Ross, L., Alexe, G., et al. (2012). The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. J Clin Invest 122, 935-947.6.Cho, J., Rameshwar, P., and Sadoshima, J. (2009). Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells. J Biol Chem 284, 36647-36658.7.Chung, Y.C., Chang, K.J., Yang, C.C., Lai, M.T., Hsu, C.P., Hsueh, S.F., Peng, C.C., Fu, H.H., Chang, Y.F., and Yang, S.D. (2002). Association of proline-directed protein kinase FA with tumorigenesis, invasion, and poor prognosis of human colon carcinoma. Cancer 95, 1840-1847.8.Fu, H.H., and Yang, S.D. (2004). Suppression of proline-directed protein kinase FA inhibits the malignant growth of human pancreatic ductal adenocarcinoma. Anticancer Res 24, 1489-1494.9.Fu, Y., Hu, D., Qiu, J., Xie, X., Ye, F., and Lu, W.G. (2011). Overexpression of glycogen synthase kinase-3 in ovarian carcinoma cells with acquired paclitaxel resistance. Int J Gynecol Cancer 21, 439-444.10.Guezguez, B., Almakadi, M., Benoit, Y.D., Shapovalova, Z., Rahmig, S., Fiebig-Comyn, A., Casado, F.L., Tanasijevic, B., Bresolin, S., Masetti, R., et al. (2016). GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia. Cancer Cell 29, 61-74.11.Hsu, C.P., Hsueh, S.F., Yang, C.C., and Yang, S.D. (2000). Suppression of proline-directed protein kinase F(A) expression inhibits the growth of human chronic myeloid leukaemia cells. Br J Cancer 82, 1480-1484.12.Hsu, C.P., Yang, C.C., Hsueh, S.F., Peng, C.C., Fu, H.H., and Yang, S.D. (2001). Suppression of proline-directed protein kinase FA potentiates apoptotic induction and greatly enhances chemosensitivity in human acute lymphoblastic leukemia cells. Cancer 92, 1753-1758.13.Hsu, C.P., Yang, C.C., and Yang, S.D. (2000). Suppression of proline-directed protein kinase FA expression potentiates erythroid differentiation of human myeloid leukemia cells. Cancer 89, 1004-1011.14.Hsu, C.P., Yang, C.C., and Yang, S.D. (2001). Suppression of proline-directed protein kinase F(A) systemically inhibits the growth of human acute leukemia cells. Int J Cancer 91, 650-653.15.Hsu, Y.C., Fu, H.H., Jeng, Y.M., Lee, P.H., and Yang, S.D. (2006). Proline-directed protein kinase FA is a powerful and independent prognostic predictor for progression and patient survival of hepatocellular carcinoma. J Clin Oncol 24, 3780-3788.16.Hsueh, S.F., Lai, M.T., Yang, C.C., Chung, Y.C., Hsu, C.P., Peng, C.C., Fu, H.H., Cheng, Y.M., Chang, K.J., and Yang, S.D. (2002). Association of overexpressed proline-directed protein kinase FA with chemoresistance, invasion, and recurrence in patients with bladder carcinoma. Cancer 95, 775-783.17.Krueger, J., Rudd, C.E., and Taylor, A. (2019). Glycogen synthase 3 (GSK-3) regulation of PD-1 expression and and its therapeutic implications. Semin Immunol 42, 101295.18.Parameswaran, R., Ramakrishnan, P., Moreton, S.A., Xia, Z., Hou, Y., Lee, D.A., Gupta, K., deLima, M., Beck, R.C., and Wald, D.N. (2016). Repression of GSK3 restores NK cell cytotoxicity in AML patients. Nat Commun 7, 11154.19.Park, S.A., Lee, J.W., Herbst, R.S., and Koo, J.S. (2016). GSK-3alpha Is a Novel Target of CREB and CREB-GSK-3alpha Signaling Participates in Cell Viability in Lung Cancer. PLoS ONE 11, e0153075.20.Taylor, A., Harker, J.A., Chanthong, K., Stevenson, P.G., Zuniga, E.I., and Rudd, C.E. (2016). Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses. Immunity 44, 274-286.21.Trowbridge, J.J., Xenocostas, A., Moon, R.T., and Bhatia, M. (2006). Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat Med 12, 89-98.22.Vidri, R.J., and Fitzgerald, T.L. (2020). GSK-3: An important kinase in colon and pancreatic cancers. Biochim Biophys Acta Mol Cell Res 1867, 118626.23.Yang, C.C., Hsu, C.P., and Yang, S.D. (2000). Antisense suppression of proline-directed protein kinase FA enhances chemosensitivity in human prostate cancer cells. Clin Cancer Res 6, 1024-1030.24.Yang, S.D. (2004). Proline-directed protein kinase FA as a potential target for diagnosis and therapy of human cancers. Curr Cancer Drug Targets 4, 591-596.
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1.Yang CC, Hsu CP, Sheu JC, Mai XY, Yang SD. Differential tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA /GSK-3α in well and poorly differentiated human prostate carcinoma cells. J Protein Chem 17: 329-335 (1998).

2.Yang SD, Yu JS, Yang CC, Lee SC, Lee TT, Ni MH, Kuan CY, Chen HC. Overexpression of protein kinase FA/GSK-3α (a proline-directed protein kinase) correlates with human hepatoma dedifferentiation/progression. J Cell Biochem 61: 238-245 (1995).

3.Lee TT, Ho YS, Yu JS, Yang SD. Overexpression of cellular activity and protein level of protein kinase FA/GSK-3α correlates with human thyroid tumor cell dedifferentiation. J Cell Biochem 58: 474-480 (1995).

4.Yang SD, Yu JS, Lee TT, Ni MH, Yang CC, Ho YS, Tsen TZ. Association of protein kinase FA/GSK-3alpha (a proline-directed kinase and a regulator of protooncogenes) with human cervical carcinoma dedifferentiation/progression. J Cell Biochem 59: 143-150 (1995).

5.Banerji, V., Frumm, S.M., Ross, K.N., Li, L.S., Schinzel, A.C., Hahn, C.K., Kakoza, R.M., Chow, K.T., Ross, L., Alexe, G., et al. (2012). The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. J Clin Invest 122, 935-947.

6.Cho, J., Rameshwar, P., and Sadoshima, J. (2009). Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells. J Biol Chem 284, 36647-36658.

7.Chung, Y.C., Chang, K.J., Yang, C.C., Lai, M.T., Hsu, C.P., Hsueh, S.F., Peng, C.C., Fu, H.H., Chang, Y.F., and Yang, S.D. (2002). Association of proline-directed protein kinase FA with tumorigenesis, invasion, and poor prognosis of human colon carcinoma. Cancer 95, 1840-1847.

8.Fu, H.H., and Yang, S.D. (2004). Suppression of proline-directed protein kinase FA inhibits the malignant growth of human pancreatic ductal adenocarcinoma. Anticancer Res 24, 1489-1494.

9.Fu, Y., Hu, D., Qiu, J., Xie, X., Ye, F., and Lu, W.G. (2011). Overexpression of glycogen synthase kinase-3 in ovarian carcinoma cells with acquired paclitaxel resistance. Int J Gynecol Cancer 21, 439-444.

10.Guezguez, B., Almakadi, M., Benoit, Y.D., Shapovalova, Z., Rahmig, S., Fiebig-Comyn, A., Casado, F.L., Tanasijevic, B., Bresolin, S., Masetti, R., et al. (2016). GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia. Cancer Cell 29, 61-74.

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11.Hsu, C.P., Hsueh, S.F., Yang, C.C., and Yang, S.D. (2000). Suppression of proline-directed protein kinase F(A) expression inhibits the growth of human chronic myeloid leukaemia cells. Br J Cancer 82, 1480-1484.

12.Hsu, C.P., Yang, C.C., Hsueh, S.F., Peng, C.C., Fu, H.H., and Yang, S.D. (2001). Suppression of proline-directed protein kinase FA potentiates apoptotic induction and greatly enhances chemosensitivity in human acute lymphoblastic leukemia cells. Cancer 92, 1753-1758.

13.Hsu, C.P., Yang, C.C., and Yang, S.D. (2000). Suppression of proline-directed protein kinase FA expression potentiates erythroid differentiation of human myeloid leukemia cells. Cancer 89, 1004-1011.

14.Hsu, C.P., Yang, C.C., and Yang, S.D. (2001). Suppression of proline-directed protein kinase F(A) systemically inhibits the growth of human acute leukemia cells. Int J Cancer 91, 650-653.

15.Hsu, Y.C., Fu, H.H., Jeng, Y.M., Lee, P.H., and Yang, S.D. (2006). Proline-directed protein kinase FA is a powerful and independent prognostic predictor for progression and patient survival of hepatocellular carcinoma. J Clin Oncol 24, 3780-3788.

16.Hsueh, S.F., Lai, M.T., Yang, C.C., Chung, Y.C., Hsu, C.P., Peng, C.C., Fu, H.H., Cheng, Y.M., Chang, K.J., and Yang, S.D. (2002). Association of overexpressed proline-directed protein kinase FA with chemoresistance, invasion, and recurrence in patients with bladder carcinoma. Cancer 95, 775-783.

17.Krueger, J., Rudd, C.E., and Taylor, A. (2019). Glycogen synthase 3 (GSK-3) regulation of PD-1 expression and and its therapeutic implications. Semin Immunol 42, 101295.

18.Parameswaran, R., Ramakrishnan, P., Moreton, S.A., Xia, Z., Hou, Y., Lee, D.A., Gupta, K., deLima, M., Beck, R.C., and Wald, D.N. (2016). Repression of GSK3 restores NK cell cytotoxicity in AML patients. Nat Commun 7, 11154.

19.Park, S.A., Lee, J.W., Herbst, R.S., and Koo, J.S. (2016). GSK-3alpha Is a Novel Target of CREB and CREB-GSK-3alpha Signaling Participates in Cell Viability in Lung Cancer. PLoS ONE 11, e0153075.

20.Taylor, A., Harker, J.A., Chanthong, K., Stevenson, P.G., Zuniga, E.I., and Rudd, C.E. (2016). Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses. Immunity 44, 274-286.

21.Trowbridge, J.J., Xenocostas, A., Moon, R.T., and Bhatia, M. (2006). Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat Med 12, 89-98.

22.Vidri, R.J., and Fitzgerald, T.L. (2020). GSK-3: An important kinase in colon and pancreatic cancers. Biochim Biophys Acta Mol Cell Res 1867, 118626.

23.Yang, C.C., Hsu, C.P., and Yang, S.D. (2000). Antisense suppression of proline-directed protein kinase FA enhances chemosensitivity in human prostate cancer cells. Clin Cancer Res 6, 1024-1030.

24.Yang, S.D. (2004). Proline-directed protein kinase FA as a potential target for diagnosis and therapy of human cancers. Curr Cancer Drug Targets 4, 591-596.

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